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Restylane®

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Interested in Restylane® and Perlane®?

Interest in hyaluronic acid-based dermafillers for facial rejuvenation in San Francisco is growing with each passing week. Restylane® is rapidly establishing a name for itself as the way to correct mid-facial wrinkles and hollows without surgery, and Perlane®, which could be described as its sister product, is gaining in popularity as well.

It's no wonder these alternatives to plastic surgery in San Francisco are gaining such momentum. Just at the time when most of us are finding it more and more acceptable—in fact, desirable—to take aggressive measures to look our best longer, time available for surgery and recovery is shrinking. The demands of family, job, and other obligations leave us scant opportunity for time out.

If you're confused by the array of dermafillers available today, don't worry. Dr. Mabrie is well acquainted with all the products and he knows which will be best to address your own individual areas of concern. To discover your options, request a consultation online or call us at (415) 445-9513 today.

Featured Cases

Case 320

Background: This young woman, in her 20's, was originally concerned with her nose. While she had long felt the tip was a little bulbous, she was certain she didn't want to have surgery.  She found Dr. Mabrie's website and after watching the videos and reviewing the before and after photos, she decided to visit San Francisco for a consultation. During her consultation Dr. Mabrie and her deci...

Case 319

Background: This Bay Area woman, in her 30's, felt she was looking older and wanted to freshen up her look. She consulted with Dr. Mabrie about Dermafillers for her under eyes. Dr. Mabrie's Assessment: "I am really excited about this case. Pretty often I see some moderate sagging of the cheek skin. I also noticed that her nose had some asymmetry to it and I felt it would really make her face look...

Case 318

Background: Woman with Eastern European background, living in the San Francisco Bay Area, had received Juvederm previously for under eye circles but wasn't happy with the outcome. She found Dr. Mabrie online and was impressed with the patient reviews. She was also impressed with Dr. Mabrie's approach and focus on non-surgical facial sculpting. She consulted with Dr. Mabrie for treatment of he...

Case 317

Background: Woman with Eastern European background, living in the San Francisco Bay Area, had received Juvederm previously for under eye circles but wasn't happy with the outcome. She found Dr. Mabrie online and was impressed with the patient reviews. She was also impressed with Dr. Mabrie's approach and focus on non-surgical facial sculpting. She consulted with Dr. Mabrie for treatment of her und...

Case 314

Background: This African American man, in his 20's, was interested in a more defined nose and overall enhanced facial appearance. He liked Dr. Mabrie's YouTube videos and decided to consult with him about Facial Dermafillers. Dr. Mabrie's Assessment: "I'm very excided about this case! It demonstrates how definition of the cheekbones and the nasal bridge and tip can positively effect the facial ap...

Case 312

Background: This woman in her 40's and mother of 2 had been considering treatment for her nose about a year. She found Dr. Mabrie online and liked the reviews and photo gallery examples. She decided to schedule a consultation in his San Francisco office. Dr. Mabrie's Assessment: "This patient was an excellent candidate for Non-Surgical Rhinoplasty. On frontal view, the contour of her nasal bridge...

Case 305

Background: This Santa Cruz woman had long felt her nose was a little round and bulbous. She liked her nose and face in general but was interested in refining her nose. She was certain she did not want a surgical procedure so when she found Dr. Mabrie's website and watched the videos and reviewed the before and after photos, she decided to visit San Francisco for a consultation. Dr. Mabrie's Asse...

Case 302

Background: This 30 year old man from Chicago discovered Dr. Mabrie's website after considering chin augmentation for some time. Encouraged by the website's helpful and detailed information and impressed by the before and after results in the website photo gallery, he flew to the San Francisco Bay Area for consultation. Dr. Mabrie's Assessment: "The upper facial features of this young...

Case 300

Background: This African American man in his 20's, had long felt his nose detracted from the rest of his face. While he liked its shape in general, he felt his nose looked too childlike. He searched for a surgeon familiar with ethnic rhinoplasty. He liked Dr. Mabrie's videos and consulted with him in his San Francisco office about Non-Surgical Rhinoplasty.   Dr. Mabrie's Assessment: In th...

Case 296

Background: This young man had considered treatment for the shadows under his eyes for quite some time. He felt he looked tired and older, and wanted to correct the dark circles. He consulted with Dr. Mabrie about Dermafillers at his San Francisco office. Dr. Mabrie's Assessment: "This patient had moderately severe dark circles under his eyes. These shadows can be especially difficult for men bec...

Case 276

Background: This young woman from the East bay wanted to subtly change the look of her nose but was not wanting surgery. She consulted with Dr. Mabrie at his San Francisco office about Non Surgical Rhinoplasty. Dr. Mabrie's Assessment: "This case illustrates the importance of a smooth nasal contour. With Rhinoplasty surgery her nose would been reduced, breaking the bone and cutting the cartilage....

Case 269

Background: This young South Bay woman was not happy with her profile, or the dark circles under her eyes. She consulted with Dr. Mabrie at his San Francisco Office about Dermafillers. Dr. Mabrie's Assessment: "I was very excited about this case. The first thing I noticed during the examination was that she had very attractive brown eyes that were competing with the shadows under her eyes. Next, ...

Case 261

Background: This East Bay woman long considered surgery to narrow her nostrils. She consulted with Dr. Mabrie at his San Francisco office regarding Surgical Rhinoplasty. Dr. Mabrie's Assessment: "I recommended Non-Surgical Rhinoplasty to augment the nasal bridge and tip, combined with an in office surgical nostril reduction." Procedure: She received 1syringe of Restylane to her nose tip and brid...

Case 237

Background: This San Francisco woman, in her 30's, had long thought about a chin augmentation procedure. She consulted with Dr. Mabrie to discuss surgical options. During the consultation they also discussed the possibility of a non-surgical procedure. Dr. Mabrie used a saline test to see if she liked the results. She did, so they decided to perform a non-surgical chin augmentation. Dr. Mabrie's ...

Case 234

Background:  This woman, in her 60's had already had a facelift over 20 years ago and didn't want to have surgery again. She was told by her surgeon that she had less bone on the left side of her face, which caused that part of her face to sag more. She was impressed with the before and after photographs she saw on Dr. Mabrie's website and decided to have a consultation with him in his San...

Case 230

Background: This Bay Area woman, in her 30's, consulted with Dr. Mabrie at his San Francisco Office about bags under her eyes. Dr. Mabrie's Assessment: "This is a good example of how important the cheeks are in treating the eyes. Augmenting her cheeks supports her eyes. In this woman's case we needed to treat both her cheeks and under her eyes, it makes her face much more youthful." Procedure:...

Case 227

Background: This east bay woman consulted with Dr. Mabrie in his San Francisco office about non-surgical Rhinoplasty. In general she was happy with the overall size and character of her nose, but wondered if some small improvements could be made. Her two main concerns: 1. She didn't want her nose to look "done". 2. She was afraid of needles!   Dr. Mabrie's Assessment: “This ca...

Case 218

Background: This young lady was fairly happy with her nose, but felt it was a little round and a little undefined. She was interested in definite changes, but nothing too drastic. She searched online for a facial plastic surgeon specializing in non-surgical Rhinoplasty in San Francisco, found Dr. Mabrie's before and afters, and made a consultation. Dr. Mabrie's Assessment: This young woman was ve...

Case 217

Background: This 56 year old San Francisco woman came in and spoke with Dr. Mabrie about getting more "fullness" lips. She felt this was important as she is still socially active in her life. Dr. Mabrie's Assesment: Dr. Mabrie suggested not only injectable Dermafillers for her lips but also for the cheeks and under eye area. He expanded dermafiller usage to other areas, so this patie...

Case 210

Background: This patient actually consulted with Dr. Mabrie about treatments under her eyes.  Dr. Mabrie noticed the nose was fairly misshapen and inquired about it.  She told him she had had a Rhinoplasty many years ago and was disappointed with the shape but really afraid of having another surgery performed. Dr. Mabrie's Assessment: Unfortunately her nose had some of the classic signs...

Case 201

Background: This woman had long considered Rhinoplasty surgery. Her nasal tip was full and similar in size and shape to the nose of her father. While she liked his nose on him, she wanted something softer and more feminine. After searching several plastic surgery websites of doctors in San Francisco, she found Dr. Mabrie and scheduled a consultation. Dr. Mabrie's Assessment: "This African America...

Case 185

Background: This San Francisco woman was becoming more physically active in her daily life. With weight loss, the patient began to notice more prominent bags under her eyes, one sign of aging. She consulted with Dr. Mabrie about her concerns. Dr. Mabrie's Assessment: "She has developed a moderate amount of volume loss to her face. This volume loss under the skin leads to lack of support under the...

Case 171

Background: San Francisco hair stylist visited Dr. Mabrie about persistent dark circles under her eyes making her look tired regardless of the amount of sleep she got.  Dr. Mabrie's Assessment: "The dark circles were caused by shadowing due to indentations under the eyes. Instead of relying on concealer we were able to fill this in with Dermafillers. In addition we discussed augmenting her c...

Case 170

Background: This 56 year old San Francisco woman came in and spoke with Dr. Mabrie about getting fuller lips. She consulted with Dr. Mabrie at his San Francisco office regarding lip augmentation. Dr. Mabrie's Assessment: Dr. Mabrie suggested not only injectable Dermafillers for her lips but also for the cheeks and under eye area. He expanded Dermafiller usage to other areas, so this patient retur...

Case 134

Background: This 35 year old postal carrier from the Northern California area traveled to see Dr Mabrie in his San Francisco office to discuss Chin Augmentation surgery. She had long considered having the procedure, but was discouraged by her family because her aunt had severe complications from a similar surgery 30 years ago. She began to notice that she was pushing her jaw forwa...

See All Before & After Photos

What Are Restylane and Perlane?

The active ingredient in both these products is hyaluronic acid, a naturally occurring substance that binds water to cells. Both work on the same principle: lifting and supporting surface skin from beneath by both filling in for lost tissue and increasing hydration. Both fillers are made by the same company, and the main difference between them is that the particles in Perlane are slightly larger.

Restylane is used to fill wrinkles and hollows in the mid and lower face, including around the lips, and can also be used for non-surgical rhinoplasty. Perlane can be used in these areas as well, and it has been widely used for lip augmentation.

Featured Videos

Are the Products Safe?

Yes, the two fillers are safe. Both are FDA-approved, and prior to their approval in the United States they had been used safely in Canada and Europe for many years.

Are There Any Side Effects?

Restylane has minimal side effects; however, some common injection-related reactions may occur, such as bruising, which is seen in about 20% of patients. Additionally, following the injection there may be swelling, which resolves within a day or two. For additional information, read what to expect during and after your treatment.

For a gentler injection procedure, Dr. Mabrie offers the innovative microcannula injection method. These blunt-ended microcannulas cut fewer arteries and veins than needles, resulting in significantly less after-treatment bruising and swelling. The microcannula technique is available upon request.

What are the Differences between Restylane and Collagen?

Unlike collagen (which lasts 3-6 months), the benefits of Perlane and Restylane treatment should be visible for 6-12 months, depending on the location of the treatment and the nature of your skin. For example, highly mobile areas like the lips tend to require at least a touch-up treatment after about 6 months. Areas where there is less movement may only require additional treatment after 12 months. Experience has shown that often, smaller amounts of Perlane and Restylane are needed for maintenance than were needed for the initial correction. Restylane is a smooth, clear gel and "flows" when it is injected and goes in very evenly.

What Is the Difference Between Perlane / Restylane and BOTOX® Cosmetic?

BOTOX Cosmetic is used in San Francisco to relax the muscles which cause many facial lines and unwanted facial expressions. Fillers like Perlane and Restylane collagen (Zyplast™ and Zyderm™), Artefill® and other products fill creases, lips, cheekbones, and also defects like acne scars. Sometimes BOTOX Cosmetic is used in combination with Perlane and Restylane when treating certain areas where permanent deep lines have resulted from overactivity of the muscles, for example some frown lines on the lower forehead or wrinkles around the lips.

Are Restylane and Perlane FDA approved?

The FDA approved Perlane and Restylane for use in the United States in 2003.

San Francisco Facial Plastic Surgeon David C. Mabrie M.D., F.A.C.S.

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The Surgeon

Dr. David Mabrie offers:

  • Double board certification
  • Excellent training & experience
  • Specialization in the face and neck
  • A trainer's skill in injectable filler techniques
Why Dr. Mabrie
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David C. Mabrie, M.D.
166 Geary Street #1502
San Francisco, CA 94108
(415) 445-9513
Dr. David Mabrie
1700 San Pablo Avenue Suite F
Pinole, CA 94564
(510) 724-3200