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Restylane®

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Interested in Restylane® and Perlane®?

Interest in hyaluronic acid-based dermal fillers for facial rejuvenation in San Francisco is growing with each passing week. Restylane® is rapidly establishing a name for itself as the way to correct mid-facial wrinkles and hollows without surgery, and Perlane®, which could be described as its sister product, is gaining in popularity as well.

It's no wonder these alternatives to plastic surgery in San Francisco are gaining such momentum. Just at the time when most of us are finding it more and more acceptable—in fact, desirable—to take aggressive measures to look our best longer, time available for surgery and recovery is shrinking. The demands of family, job, and other obligations leave us scant opportunity for time out.

If you're confused by the array of dermal fillers available today, don't worry. Dr. Mabrie is well acquainted with all the products and he knows which will be best to address your own individual areas of concern. To discover your options, request a consultation online or call us at (415) 445-9513 today.

Featured Cases

Case 325

ABOUT OUR PATIENT After doing some research about noninvasive cosmetic surgery online, this young man from Brazil stopped by my San Francisco office for a consultation. He had a clear vision of what he wanted to improve-his nose. He wanted to remove a small distracting bump and make the tip appear more upturned. Facial dermal filler treatments are ideal for these kinds of aesthetic defects, so I ...

Case 322

Background: This East Bay man, in his 50's, wanted  improvement of his under eyes and facial collapsing but did not want to look overdone. He consulted with Dr. Mabrie in his Pinole office about Facial Dermafillers. Dr. Mabrie's Assessment: "He had  severe volume loss! In the past I would have used Radiesse to replace the loss because of the heaviness of the skin that we see in both mal...

Case 320

ABOUT OUR PATIENT Originally concerned about the shape of her nose, this young woman from California in her 30's was seeking non-surgical alternatives for treatment. Having spent time researching what options were available to her, she found my website and watched some of my informational videos. As soon as she was finished, she set up a consultation at my San Francisco office where we discussed ...

Case 318

ABOUT OUR PATIENT This young Bay Area woman had previously received a non-surgical Juvederm treatment to address the circles that were appearing under her eyes, but she wasn't exactly satisfied with the results. After reading some of my patient reviews online and noting my unique approach and focus on non-surgical facial sculpting, she decided to come in for a consultation at my downtown San...

Case 317

ABOUT OUR PATIENT This young Bay Area woman had previously received a non-surgical Juvederm treatment to address the circles that were appearing under her eyes, but she wasn't exactly satisfied with the results. After reading some of my patient reviews online and noting my unique approach and focus on non-surgical facial sculpting, she decided to come in for a consultation at my downtown San Fran...

Case 314

ABOUT OUR PATIENT This patient of mine is an African American man in his 20's. He stated becoming interested in non-surgical cosmetic procedures after deciding that he wanted a more defined nose and enhanced facial appearance. After seeing some of my YouTube videos online, he came into our San Francisco office for a consultation to find out how using facial dermal fillers could significantly tran...

Case 312

ABOUT OUR PATIENT For about a year, this 40-something mother of two had thought about getting a treatment for her nose. She started doing research about her options and came across the reviews and photos for my cosmetic surgery practice. Soon after, I was glad to welcome her to my San Francisco office where I gave her an in-depth consultation. DR. MABRIE'S TREATMENT PLAN For this patient, I per...

Case 305

ABOUT OUR PATIENT This woman from Santa Cruz really liked the way her face looked in general but was interested in refining her nose. She felt it was a little round and slightly bulbous in appearance. Evan so, she knew she definitely did not want an invasive surgical procedure to fix it. When she found my website, watched our videos, and reviewed the before and after photographs, she decided to v...

Case 300

ABOUT OUR PATIENT This African American man in his 20's had a big problem: he had long felt his nose detracted from the rest of his face. While he appreciated its shape in general, he felt it made him look too childlike. During his search for a surgeon experienced in Ethnic Rhinoplasty, my videos caught his eye, so we met in my downtown San Francisco office, where I consulted with him about non...

Case 296

ABOUT OUR PATIENT After considering under eye treatment for quite some time, this young man from California felt he looked tired and older than her felt, and wanted to get rid of his dark under eye circles. I was happy to consult with him when he stopped into my San Francisco Bay Area office. DR. MABRIE'S TREATMENT PLAN This patient had moderately severe dark circles under his eyes. These shado...

Case 276

ABOUT OUR PATIENT This patient, a young woman located in the East Bay, had a common problem: she wanted to subtly change the look of her nose, but she didn't want to undergo any invasive surgery to do so. That's why she came to see me at my San Francisco office for a consultation, eager to find out about the benefits of Non-Surgical Rhinoplasty. DR. MABRIE'S TREATMENT PLAN This patient's case i...

Case 269

ABOUT OUR PATIENT This patient of mine, a young woman from the South Bay in California, wasn't feeling too happy with her profile, or the dark circles that were creeping up beneath her eyes. She came to my San Francisco office for a consultation, specifically asking about the possibilities that Dermal Fillers could provide. The first thing I noticed during our examination was that she had very a...

Case 268

Background: This California man received Juvederm 2 years earlier and developed bagginess and a slight blue tint. He originally consulted with Dr. Mabrie in his San Francisco office about eyelid surgery. After examination, Dr. Mabrie recommended dissolving the Juvederm under the eyes and replacing it with Restylane. Dr. Mabrie's Assessment: "Some of the filler previously placed was too superficia...

Case 261

ABOUT OUR PATIENT I love this case! This woman in her 70s from the East Bay, had long considered getting surgery to narrow her nostrils. She and I had a great talk during a consultation in my San Francisco office regarding Surgical Rhinoplasty, in which we explored options that would get her the amazing results she was after. DR. MABRIE'S TREATMENT PLAN I performed a Non-Surgical Rhinoplasty us...

Case 237

Background: This San Francisco woman, in her 30's, had long thought about a chin augmentation procedure. She consulted with Dr. Mabrie to discuss surgical options. During the consultation they also discussed the possibility of a non-surgical procedure. Dr. Mabrie used a saline test to see if she liked the results. She did, so they decided to perform a non-surgical chin augmentation. Dr. Mabrie's ...

Case 234

ABOUT OUR PATIENT After having a facelift over 20 years ago, this California woman in her 60's told herself she wasn't going to have surgery again. Her previous surgeon told her that she didn't have enough bone on the left side of her face, so the sagging she was experiencing was "permanent". After browsing through the before and after photographs she saw on my website, and checking out the amazi...

Case 230

ABOUT OUR PATIENT Developing bags under your eyes is a common sign of aging that can be easily remedied with the use of facial Dermal Fillers. This particular patient of mine, from Northern California, approached me about the bags she started seeing beneath her eyes. She visited my office located in the heart of the San Francisco Bay Area, and we discussed non-invasive, non-surgical cosmetic so...

Case 221

Background: This woman was primarily concerned with her profile. She felt the curvature was extreme and made the nose seem large. She found Dr. Mabrie online and consulted about non-surgical treatmen.  Dr. Mabrie’s Assessment: “This was a very satisfying case. We both agreed that her concerns were slightly different from many of the cases previously seen in my photo gallery....

Case 218

ABOUT OUR PATIENT This young lady was already feeling somewhat satisfied with the shaping of her nose, but she knew there was room for improvement. She felt it looked a little round and slightly undefined. Basically, she was looking for a change that was defining but not too drastic. After searching online for a facial plastic surgeon specializing in Non-Surgical Rhinoplasty, she found our before...

Case 217

ABOUT OUR PATIENT "How can I get fuller lips?" As you can probably guess, I hear that question a lot. The answer is different each time, since each patient I help has a unique facial structure. This woman from the Bay Area, in particular, asked me about her lips when she came in for a consultation at my office in downtown San Francisco. We discussed the many benefits and options for Lip Augm...

Case 210

ABOUT OUR PATIENT This patient initially visited my San Francisco office interested in finding the right kind of filler treatment for bags under her eyes. I noticed her nose was somewhat misshapen and injured as well. She told me it was the result of a Rhinoplasty she had many years ago. There has been a hump reduction during the Rhinoplasty surgery, which had caused the middle cartilaginous port...

Case 201

Background: This woman had long considered Rhinoplasty surgery. Her nasal tip was full and similar in size and shape to the nose of her father. While she liked his nose on him, she wanted something softer and more feminine. After searching several plastic surgery websites of doctors in San Francisco, she found Dr. Mabrie and scheduled a consultation. Dr. Mabrie's Assessment: "This African America...

Case 185

ABOUT OUR PATIENT This woman from San Francisco had become more physically active in her daily life. As she achieved a higher level of fitness, she began to notice more prominent bags under her eyes. As you know, that's one of the telltale signs of aging. She made the decision to come in and talk with me about how to make them less apparent, so her facial features would be in harmony with how she...

Case 171

ABOUT OUR PATIENT A successful hair stylist in San Francisco, this patient came in to see me about persistent dark circles under her eyes. These circles caused her to look tired no matter how much sleep she tried to get every night. This is a common concern for most patients who come to see me for a consultation, so I had plenty of non-surgical solutions to offer her. These dark circles were bei...

Case 170

ABOUT OUR PATIENT "How can I get fuller lips?" As you can probably guess, I hear that question a lot. The answer is different each time, since each patient I help has a unique facial structure. This woman from the Bay Area, in particular, asked me about her lips when she came in for a consultation at my office in downtown San Francisco. We discussed the many benefits and options for Lip Augmentat...

See All Before & After Photos

What Are Restylane and Perlane?

The active ingredient in both these products is hyaluronic acid, a naturally occurring substance that binds water to cells. Both work on the same principle: lifting and supporting surface skin from beneath by both filling in for lost tissue and increasing hydration. Both fillers are made by the same company, and the main difference between them is that the particles in Perlane are slightly larger.

Restylane is used to fill wrinkles and hollows in the mid and lower face, including around the lips, and can also be used for non-surgical rhinoplasty. Perlane can be used in these areas as well, and it has been widely used for lip augmentation.

Featured Videos

Are the Products Safe?

Yes, the two fillers are safe. Both are FDA-approved, and prior to their approval in the United States they had been used safely in Canada and Europe for many years.

Are There Any Side Effects?

Restylane has minimal side effects; however, some common injection-related reactions may occur, such as bruising, which is seen in about 20% of patients. Additionally, following the injection there may be swelling, which resolves within a day or two. For additional information, read what to expect during and after your treatment.

For a gentler injection procedure, Dr. Mabrie offers the innovative microcannula injection method. These blunt-ended microcannulas cut fewer arteries and veins than needles, resulting in significantly less after-treatment bruising and swelling. The microcannula technique is available upon request.

What are the Differences between Restylane and Collagen?

Unlike collagen (which lasts 3-6 months), the benefits of Perlane and Restylane treatment should be visible for 6-12 months, depending on the location of the treatment and the nature of your skin. For example, highly mobile areas like the lips tend to require at least a touch-up treatment after about 6 months. Areas where there is less movement may only require additional treatment after 12 months. Experience has shown that often, smaller amounts of Perlane and Restylane are needed for maintenance than were needed for the initial correction. Restylane is a smooth, clear gel and "flows" when it is injected and goes in very evenly.

What Is the Difference Between Perlane / Restylane and BOTOX® Cosmetic?

BOTOX Cosmetic is used in San Francisco to relax the muscles which cause many facial lines and unwanted facial expressions. Fillers like Perlane and Restylane collagen (Zyplast™ and Zyderm™) and other products fill creases, lips, cheekbones, and also defects like acne scars. Sometimes BOTOX Cosmetic is used in combination with Perlane and Restylane when treating certain areas where permanent deep lines have resulted from overactivity of the muscles, for example some frown lines on the lower forehead or wrinkles around the lips.

Are Restylane and Perlane FDA approved?

The FDA approved Perlane and Restylane for use in the United States in 2003.

San Francisco Facial Plastic Surgeon David C. Mabrie M.D., F.A.C.S.

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The Surgeon

Dr. David Mabrie offers:

  • Double board certification
  • Excellent training & experience
  • Specialization in the face and neck
  • A trainer's skill in injectable filler techniques
Why Dr. Mabrie
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David C. Mabrie, M.D.
166 Geary Street #1502
San Francisco, CA 94108
(415) 445-9513
Dr. David Mabrie
1700 San Pablo Avenue Suite F
Pinole, CA 94564
(510) 724-3200