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Mabrie Facial Institute
166 Geary Street
Floor 1300
San Francisco, CA 94108
Phone: (415) 445-9513
Text/SMS: (866) 618-9459
Monday–Friday 8 a.m.–5:30 p.m.
A New Kind of Injectable
Mabrie Facial Institute was among the first practices in San Francisco, California, to recognize PRF EZ Gel’s role in modern regenerative aesthetics. Made from your own blood and rich in concentrated growth factors, PRF EZ Gel offers a more natural approach to injectable rejuvenation. Its soft, gel-like consistency is ideal for delicate concerns such as under-eye hollows, fine lines, thin or crepey skin, and early soft-tissue changes.
As part of our i360 Natural Refresh service, PRF EZ Gel helps improve skin quality and tissue resilience while preserving the structure, balance, and luminosity central to our Illumination 360˚® approach. We may recommend it on its own when the priority is subtle skin rejuvenation, or pair it with traditional filler when the plan calls for both tissue renewal and structural support.

What Is PRF EZ Gel?
PRF EZ Gel is an injectable treatment made from your own blood. We draw a small sample, process it to concentrate platelets and growth factors, then use a gentle heating and cooling process to transform it into a gel. The result is a 100% natural treatment that supports collagen production, improves tissue quality, and softens early signs of aging.
How Is PRF EZ Gel Different From Traditional PRF Treatments?
PRF EZ Gel starts with the same regenerative foundation as traditional PRF, but the gel preparation gives our Injectors greater control, more targeted placement, and a more refined way of supporting facial rejuvenation.
Traditional PRF
- Fluid, injectable PRF
- Diffuses more broadly within the tissue
- Useful for general regenerative rejuvenation
- Supports skin quality, healing, and collagen activity over time
- Spreads more broadly after injection
- Often used when the goal is overall skin rejuvenation
PRF EZ Gel
- Smooth, gel-like injectable PRF
- Allows more controlled placement in targeted areas
- Ideal for delicate areas where softness and precision matter
- Improves tissue quality while adding gentle, natural-looking volume
- More suited to precise, layered correction
- Often used when the goal is delicate correction with a natural feel
By combining regenerative biology with improved structure and control, PRF EZ Gel gives our Injectors a more precise way to address skin quality and early soft-tissue changes in delicate areas.
A Different Treatment for a Different Goal
Think of PRF EZ Gel as an alternative—but not a replacement—to hyaluronic acid-based fillers such as JUVÉDERM® and Restylane®.
While these fillers shape and sculpt the contours of your face, i360 Natural Refresh with PRF EZ Gel supports your tissue quality from within, improving skin tone, texture, and subtle volume over time. It’s a restorative approach that aligns seamlessly with MFI’s philosophy: enhancement that looks and feels inherently natural.

| PRP vs PRF vs EZGel | PRP Platelet-Rich Plasma | PRF Platelet-Rich Fibrin | EZGel PRF |
|---|---|---|---|
| Additives | Processed with additives / anticoagulants | None — 100% natural | None — 100% natural |
| Consistency | Thin liquid | Thicker fibrin liquid | Soft gel |
| Growth Factors | Release quickly | Release gradually | Gradual & sustained release |
| Results | Subtle and more temporary | Gradual improvement | Subtle support + gradual improvement |
| Best Used | Microneedling for skin glow and quality, hair restoration | Under eyes, skin rejuvenation | Lips, under eye, nasolabial folds, cheeks |
Important to understand: EZ Gel is a subtle, gradual treatment. It does not contour or add structural volume like traditional HA filler.
Results rely on your body’s own healing and collagen response — they vary from person to person and build slowly over time.
Who Is a Good Candidate for PRF EZ Gel?
PRF EZ Gel works well for patients looking for a natural approach to facial rejuvenation, especially if you’re noticing early signs of aging like fine lines, thinning or crepey skin, or mild volume loss. It can also complement filler and BOTOX® treatments by improving the quality of the surrounding skin, helping your results look smoother, softer, and more naturally refreshed over time.
At MFI, we use our Illumination 360˚ Facial Analysis to evaluate your face from every angle before recommending any treatment. PRF EZ Gel may be recommended on its own or alongside other treatments, depending on your individual goals.
What to Expect in the Office
Plan for approximately 2 hours with us. Here is your step-by-step experience:
| 1 | Cleanse | Arrive with no makeup |
|---|---|---|
| 2 | Photos | To document results |
| 3 | Blood Draw | Small draw: similar to a routine lab test |
| 4 | Centrifuge | Blood is spun to isolate healing platelets, fibrin, and growth factors |
| 5 | EZGel creation | PRF transformed into a smooth gel |
| 6 | Treatment | Gel is injected into your target areas |
| 7 | Aftercare | We walk you through your recovery plan |
Benefits of PRF EZ Gel
PRF EZ Gel offers unique advantages for patients seeking a refined, conservative approach to skin and soft-tissue rejuvenation. Its value lies in how gently it integrates, how gradually it improves the treated areas, and how well it can be incorporated into a personalized injectable plan.
We love PRF EZ Gel because of its:
- 100% natural formulation: Because PRF EZ Gel is autologous (derived from your body), it may be appealing to patients who prefer to avoid synthetic injectable products when appropriate.
- Gradual, regenerative results: Results develop over time as the treatment encourages healthier-looking skin and improved tissue quality.
- Soft, natural integration: PRF EZ Gel is often chosen for areas where softness, precision, and natural movement are especially important.
- Versatile application: We can use PRF EZ Gel to treat mild hollowness, fine lines, crepey texture, or thinning skin.
Together, these benefits make PRF EZ Gel a compelling option for patients who want visible improvement through a softer, more gradual approach.
Why Choose MFI for PRF EZ Gel?
MFI approaches PRF EZ Gel with the same precision, restraint, and aesthetic discipline that define our injectable work. For us, innovation is not about adding the newest treatment to the menu but recognizing when a technique offers a meaningful, reliable role within a larger facial rejuvenation plan.
Because PRF EZ Gel works differently from traditional fillers, it requires a provider who understands not only what it can improve, but where its benefits are most useful. That’s why PRF EZ Gel is always thoughtfully matched to the right patient and treatment goals.
The result is a rejuvenation plan that uses PRF EZ Gel for a clear purpose—not as a trend or filler replacement, but as one carefully chosen element in a balanced, natural-looking refresh.
The MFI Advantage
MFI focuses exclusively on injectables and has set the bar in the art and science of fillers for more than 15 years. Dr. Mabrie, trained as a facial plastic surgeon, has dedicated thousands of hours to refining the most innovative, effective, and safe techniques for injectables. There is no other practice in the Bay Area with the level of experience, education, and passion for injectables you’ll find at MFI.
Schedule MeAreas of Refinement
We use PRF EZ Gel in areas where traditional fillers alone may not fully address concerns, such as:
- Under-eye hollows and crepey skin
- Lips and fine lines around the mouth
- Skin thinning or early volume loss
- Areas requiring subtle, layered refinement
Each application is guided by a comprehensive facial assessment, not a one-size-fits-all approach.
How Much Does PRF EZ Gel Cost?
The price of PRF EZ Gel injections depends on the treatment area, the amount needed to address your concerns, and whether it is being combined with other treatments. Please call or check our Procedure Pricing page for current pricing.
PRF EZ Gel FAQs
How long do results from PRF EZ Gel last?
PRF EZ Gel does not last as long as many traditional dermal fillers and usually requires a series of treatments spaced about 4 to 6 weeks apart. Rather than acting as a long-lasting volumizer, PRF EZ Gel supports gradual improvement in skin quality, tone, and soft-tissue refinement. Ongoing maintenance is typically recommended for best results.
Can PRF EZ Gel be stored for future treatments?
No. PRF EZ Gel must be used immediately after it is prepared. Because it is derived from your own blood and processed fresh at the time of your appointment, it cannot be stored or preserved for later use. This freshness helps preserve the active growth factors that make the treatment effective.
Will my results be consistent from one treatment to the next?
PRF EZ Gel is made from your own blood, so outcomes can vary slightly from one treatment to the next. Factors such as hydration, overall health, and individual biology can influence the concentration of platelets and growth factors obtained during the blood draw.
How is PRF EZ Gel different from traditional dermal fillers?
While traditional fillers are designed to create structure and add immediate volume, PRF EZ Gel works by stimulating your body’s own regenerative processes. It improves skin quality, texture, and subtle volume over time, making it an ideal complement to structural treatments with fillers.
Is PRF EZ Gel a good option for under-eye rejuvenation?
PRF EZ Gel is especially well-suited for delicate areas like the under eye, where skin quality and thinness are often the primary concerns. Its soft, smooth quality allows for refined improvement in hollows, crepey texture, and discoloration without the risk of looking overfilled.
We’d Love To See You
For patients considering PRF EZ Gel injections in the San Francisco Bay Area, Mabrie Facial Institute offers more than a new regenerative treatment. We offer a discerning, full-face approach that is guided by our proprietary Illumination 360® philosophy. Request a consultation onlinewith one of our Injectors, or call us at (415) 445-9513 to schedule your initial appointment.

