Have you ever wondered if you can remove or reverse dermal fillers? At Mabrie Facial Institute in the San Francisco Bay Area, flexibility is one of our favorite things about fillers, so we offer the option of reducing or reversing them. Most of our fillers—specifically hyaluronic acid-based fillers—can be reversed with injections of a substance called Hylenex.

This product instantly dissolves fillers such as JUVÉDERM and Restylane products if you are unhappy with your results or you simply want less volume. Because our Injectors “layer” fillers over the course of 2 appointments, it is rare that our patients want or need to have their fillers reversed. However, Hylenex gives us even greater options when it comes to refining your results to near perfection.

What Is Hylenex?

Hylenex is an injectable product comprised of hyaluronidase—an enzyme that helps the body break down and disperse hyaluronic acid. Hyaluronic acid is the main component of most of the fillers we use at Mabrie Facial Institute. Hylenex will not work on RADIESSE, but works on all the products in the JUVÉDERM and Restylane families.

See how Hylenex works in this video:

How Do I Know if I Need Hylenex?

Most patients at Mabrie Facial Institute are very happy with their filler treatments, and very few require Hylenex. However, we do routinely treat individuals who are unhappy with filler results from other practices. Indications for the use of Hylenex include:

  • Overfilled, unnatural looking lips
  • Visible filler in the under-eye area (Tyndall effect)
  • Filler causing vascular occlusion in the nose

Since swelling is common after filler treatment, it’s best to wait at least 2 weeks before deciding whether you want your fillers dissolved.

Hylenex and Your Safety

One of the reasons we have Hylenex at our disposal is as a safety precaution. One of the rare risks involved with dermal fillers is a complication called vascular occlusion. This is when an artery or vein is blocked by filler, restricting blood flow to the tissues in the area. This can quickly lead to tissue necrosis (death) if it isn’t recognized and treated quickly. This risk is somewhat higher in nonsurgical rhinoplasty, or when an injector is not extremely familiar with the vascular anatomy of the treatment area.

At Mabrie Facial Institute, we have the experience and training to generally avoid complications like vascular occlusion. However, that experience and training also enable us to look for and identify signs of vascular occlusion, and immediately dissolve the filler with Hylenex if there is any risk.

I'm a Top 25 Most Loved Injector

Out of 2,000 nominees in the U.S., Dr. Mabrie was voted one of the Top 25 Most Loved Injectors for 2017 by the RealSelf community. Thanks to all our amazing patients for making him the only injector in the Bay Area to receive this honor.

How Much Does Hylenex Cost?

Hylenex starts at $970. For accurate, up to date pricing, visit our Fees & Financing page.

The Team at
Mabrie Facial Institute

Our team is made up of experienced medical professionals with a shared passion for facial rejuvenation and contouring with injectables. Hand-picked and trained by Dr. Mabrie in the Illumination 360° approach, they work with you to create a treatment experience that exceeds your expectations.

We’d Love To See You 

Find out why so many women and men choose Mabrie Facial Institute for Hylenex treatment in the San Francisco Bay Area. Request a consultation online with one of our Injectors, or call us at (415) 445-9513 to schedule your initial appointment. If you’ll be visiting us from outside the area, our Fly in for Your Procedure page was created just for you to help make planning your trip as smooth as possible.

A Reputation Built on Results

You deserve the highest caliber of service, care, and results, and at Mabrie Facial Institute, we're committed to providing all that and more. But don't take our word for it—see for yourself what our actual patients have to say about their experiences with us.

Read More Patient Reviews
Google
5.0/5
Jul 27, 2021
Google Mabrie Facial Institute
I love this place they treat everybody so friendly and i love the environment. This is definitely my go to if I need a touch up!!
Google
5.0/5
Apr 6, 2021
Google Mabrie Facial Institute
Loving my results so far! I can't wait to come back again! The staff was so friendly and made me feel welcomed and very safe. The office is beautiful and clean! I was immediately greeted and did a COVID screening with a temp check. They escorted me to my room with a beautiful view of SF. I felt pampered, and their customer service is excellent! The injector Tiffany answered all my questions and made me feel at ease, since this was my first time getting Botox. After she marked my face, she explained where and why she was placing the Botox in certain areas. My frown muscles were so bulky and I didn't like how it always looked like I was frowning even when my face was at rest. Now, I don't always look like I'm frowning! My frown muscles look less bulky, forehead looks smoother and I got a subtle brow lift -- I love it!
Facebook
5.0/5
Mar 29, 2021
Facebook Mabrie Facial Institute
Very comfortable coming here. Love the remodel they did in their new office. Of course Dr. Mabrie skills are becoming legendary.
Facebook
5.0/5
Feb 19, 2021
Facebook Mabrie Facial Institute
Dr. Mabrie and his staff are so welcoming, reassuring and most of all skilled at making you look your best. Great location and groovy vibe to the office overlooking Union Square. I got the Illuminate 360 because I deserve it!
Facebook
5.0/5
Jan 13, 2021
Facebook Mabrie Facial Institute
They are amazing here w/ customer service, amiable, listen fully to your desires, and work their hardest to bring them to fruition whether it’s the initial appointment or in my case, complementary touch up w/in set timeframe. Just for clarification, when I put “they” I mean everyone from whomever answers the phone/anyone greeting you when the elevator’s doors open and you arrive at your appointment to your departure via the elevator again. Side note: I would include the security/door men as they’ve always been pleasant to me, but they aren’t apart of this business🙂
Facebook
5.0/5
Nov 18, 2020
Facebook Mabrie Facial Institute
I've never had anything done before this. Everyone at Dr. Marbrie office made me feel right at home. I loveeee the work they did and Kim is the BEST! THANKS GUYS!!
Google
5.0/5
Nov 18, 2020
Google Mabrie Facial Institute
For my first time ever getting work done on my face, this was a great experience. They made me feel at home and comfortable which eased my fear. I got my mid-area done by Kimberly and it looks amazing. I can’t wait to fly back out there for my second session! If your looking to have work done I highly recommend them, you’ll be happy you did.
Facebook
5.0/5
Sep 29, 2020
Facebook Mabrie Facial Institute
I came in earlier today and got a 360 facial treatment done. Everyone in the office made me feel really comfortable. It’s a really lovely space and it’s chic but really homey. I definitely would go back and I feel safe with the results. I feel like Dr. Mabrie was very transparent about the pricing and what he would be using and where. I do still have some swelling in my chin mainly. But excited to see what it looks like when I’m healed!
RateMDs
3.3/5
Aug 25, 2020
RateMDs Mabrie Facial Institute
I really like the staff here however Dr. Mabrie has one of those egoic attitudes. He is good at his job and he knows it. However, he doesn't seem interested in his patients. I have been there several times and I just kind of deal with it. I just wish he acted like he cared about his clients.
Google
5.0/5
Aug 3, 2020
Google Mabrie Facial Institute
Dr. Mabrie is a wizard. After extensive research across California (SF to LA and everywhere in between) for who to consult for some of my skin concerns, I chose this clinic for Dr. Mabrie's multi-faceted expertise and reviews on meticulousness. I wasn't shorted, him and his team are incredible.
Google
5.0/5
Jul 8, 2020
Google Mabrie Facial Institute
I've visited Mabrie Facial Institute twice, and both visits were stellar. All staff members, from the font-line staff, to assistants, all the way up to Dr. Mabrie were kind, caring, thoughtful- I honestly just can't say enough. At no time did I feel pressured about anything. Honestly (and trust me, I'm skeptical of most people), everyone there made me feel appreciated and cared for. They were patient with my endless questions, did very careful work, and were just overall so lovely and personable. I've honestly never had such a great experience before.
Facebook
5.0/5
Mar 5, 2020
Facebook Mabrie Facial Institute
Dr David Mabrie He is amazing 😘
Facebook
5.0/5
Mar 2, 2020
Facebook Mabrie Facial Institute
Best face guy around. Full stop.
Google
5.0/5
Feb 13, 2020
Google Mabrie Facial Institute
I first came across Dr. Mabrie’s practice when I was reviewing the top 100 US aesthetic injectors list for 2019. While I had been to other offices in LA and NYC, I had been dying to go someplace in The Bay (where I live). Finally I had found a practice where I could draw up a beauty plan and see tangible, top of the line results. Fast forward to 2020 and I’m on my second visit with Kimberly for lower face enhancement and masseter slimming with Botox. The warmth, professionalism, and artistic vision of Kimberly and the Mabrie team is unparalleled — I highly recommend if you’ve been considering any type of cosmetic beautification, that you jump right into the chair at Mabrie Facial Cosmetics. Thanks again Mabrie team!! I love my results, and can’t wait to see you again in just a month’s time.
Google
5.0/5
Feb 5, 2020
Google Mabrie Facial Institute
Dr. Mabrie is the most skilled filler doc in the bay area! He's so skilled and transparent about pricing. Also, his office is beautiful and the staff are so friendly. Highly recommend!!
Google
5.0/5
Jan 30, 2020
Google Mabrie Facial Institute
Previously, I've used online coupons offers which slightly improved my sunken eye look, as well as the furrows on my brow and mouth. After receiving Dr. Mabrie's facial treatment, my husband who hadn't been too impressed with my coupon treatments, immediately said, "WowI Baby, you look so beautiful!" I cannot give a greater testimonial than that. And I too share my husband's sentiment - I do look damn amazing! 🙂
Google
5.0/5
Jan 29, 2020
Google Mabrie Facial Institute
I have been going to Dr. Mabrie for probably seven years and I look better than ever! I saw his online discussions of his techniques and decided, this is the doctor for me! I have not been disappointed and it's definitely worth my 2.5-3 hour drive to San Francisco to get my treatments. He and his entire staff are excellent!
Google
5.0/5
Jan 28, 2020
Google Mabrie Facial Institute
I’m so happy with my results! Excellent service, David Mabrie and his team are awesome. I’m certainly coming back for a refinement treatment and touch ups in 9-12 months time. Thank you !!!!
Facebook
5.0/5
Jan 22, 2020
Facebook Mabrie Facial Institute
If you’re interested in looking younger, or you feel self conscious about any particular part of your own face, GO SEE Dr. Mabrie! You won’t ever regret seeing this amazing, compassionate, incredibly talented and intelligent Doctor. He has changed so many lives, and he will make yours better too.
Google
5.0/5
Dec 3, 2019
Google Mabrie Facial Institute
Truly, the best practitioner in the Bay Area, and one who keeps up to date on new developments in the field. Since 2017, when I first went to see Dr Mabrie after noticeable loss of volume in my face, he's carefully restored me back to my younger appearance. He doesn't ever suggest unnecessary treatments or over-inject; he's not cheap (nothing in San Francisco is), but his expert approach to fillers guarantees very natural-looking results that will elicit "Oh, you're looking so great!" comments, rather than the dreaded "Got some work done, huh?" Highly recommend him!
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