A game-changing product in facial aesthetics, KYBELLA helps men and women achieve a refined look by eliminating fat from the chin and neck line — without surgery. Also called the “double chin injection,” KYBELLA treatments in San Francisco from Dr. David C. Mabrie are a simple way to treat one of the most stubborn concerns in the cosmetic enhancement industry. Dr. Mabrie is known for his expertise in non-surgical facial rejuvenation, and KYBELLA injections are a safe, effective tool to enhance your natural attractiveness.

Learn how Dr. Mabrie customizes dermal filler treatments to reveal Your Perfect Face—the one that looks great from any angle, in any light.

Your Treatment Starts Here


KYBELLA is the first and only injectable drug approved by the FDA to reduce fat beneath the chin — known clinically as submental fat but usually called a double chin. Although a double chin is a common cosmetic concern, it often goes untreated because it previously required a surgical procedure, such as facial liposuction. Patients who prefer a non-surgical alternative now have a choice with KYBELLA.

It’s formulated using a synthetic version of a chemical naturally produced by the body that helps absorb and process dietary fat. The chemical, deoxycholic acid, destroys fat when it’s injected in the area beneath the chin. The destroyed fat cells are flushed from your body over time, leaving you with a slim, contoured chin and neck.

What to Expect

Dr. Mabrie customizes treatments based on your unique anatomy. Your personalized consultation includes a discussion of your aesthetic goals and a thorough physical examination. Once he determines that a non-surgical approach to enhance your chin and neck is appropriate, Dr. Mabrie creates a precise treatment plan.

Because each KYBELLA treatment session includes multiple injections, he marks a detailed grid on your skin showing the specific injection sites. Most treatments include 20 to 30 quick injections, although up to 50 injections are possible. A topical anesthetic is applied to help maintain your comfort during the treatment.

Most patients begin seeing results after 2 to 4 treatment sessions, spaced about a month apart. Up to 6 treatment sessions may be needed to achieve the optimal results. Because KYBELLA destroys the fat cells, they can no longer store or accumulate fat, meaning KYBELLA is considered a permanent treatment.

What Does KYBELLA Cost?

Because each treatment is tailored to a patient’s specific needs, the cost of KYBELLA treatments varies. The number of injections performed during each treatment session and the total number of sessions needed to get the desired results determine the total cost. As with other cosmetic procedures, additional factors affecting the price of treatments include the geographic area where the procedure is performed and the experience of the provider.

Although price is always something to consider, selecting a skilled facial plastic surgeon who specializes in nonsurgical rejuvenation is extremely important.

Are There Side Effects?

Throughout the multiple clinical trials leading to KYBELLA’s approval by the FDA, the most common side effects were the same as seen in most injectable procedures. Minor bruising, swelling, and redness are typical and diminish after a few days. Numbness, pain, and hardness in the area of the injections are other temporary side effects that may occur.

Learn more about KYBELLA and whether it’s an appropriate treatment for you by requesting a consultation online to meet with Dr. Mabrie, or call our office at (415) 445-9513 to schedule an appointment.

Dr. David Mabrie

For more than a decade, Dr. David Mabrie has been perfecting his technique for optimizing facial beauty with dermal fillers. He is the only facial plastic surgeon in San Francisco whose practice is focused entirely on injectables.